mean reentrant gain -0.265382 +/- 0.000001 with 95% CI [-0.265384, -0.265380], mean score +0.064109 +/- 0.000002, mean healthy fraction +0.515540 +/- 0.000001, mean resistant fraction +0.321737 +/- 0.000001, mean switch rate +0.045083 +/- 0.000000, and threshold 0.35 selected in 0.0% of completed trials; every reentrant-gain summary was uniformly negative across 134 completed payloads.
The proposed delay-fatigue switch does not create a reentrant efficacy window in the antibiotic-control landscape. System-level health and resistance observables are extremely stable across seeds, but the stability is centered on a monotone penalty rather than a mid-threshold optimum. Because the best-threshold selector never concentrates on 0.35 and the reentrant statistic is negative in every completed payload, the apparent structure is algorithmic rigidity rather than a biologically meaningful switch point. The implication is that fatigue and delay are not balancing each other here; they jointly move the system away from the hypothesized intermediate-control regime.
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